Enhancing Trustworthiness of Qualitative Findings: Using Leximancer for Qualitative Data Analysis Triangulation

This paper offers an approach to enhancing trustworthiness of qualitative findings through data analysis triangulation using Leximancer, a text mining software that uses co-occurrence to conduct semantic and relational analyses of text corpuses to identify concepts, themes, and how they relate to one another. This study explores the usefulness of Leximancer for triangulation by examining 309 pages of previously analyzed interview data that resulted in a conceptual model. Findings show Leximancer to be an ideal tool for refining a priori conceptual models. The Leximancer analysis provided missing nuance from the a priori model, depicting the value of and connection between emergent themes. Dependability was also added to the findings by facilitating a better understanding of how participant quotes represent particular themes

Breakout Session: Paths to Obtaining Funding for Community Engaged Research

Discusses the UMass CCTS Community Engagement & Research Section Pilot/Feasibility Grants Program and other potential sources of funding for community engaged research

A Community-Based Social Networking Intervention to Increase Walking in Dog Owners

Roughly 40% of U.S. households own a dog and while dog ownership is associated with greater engagement in physical activity, up to 60% of dog owners do not achieve the recommended 150 minutes of weekly physical activity. The present study aims to develop and test a dog walking intervention addressing individual, interpersonal, and community factors. The study represents collaboration between UMass Medical School, UMass Lowell and their community partners, Common Pathways and the Greater Lowell Health Alliance. The developmental phase uses a community-based participatory research approach by creating community advisory boards and conducting focus groups with residents to ensure community perspectives are represented throughout intervention development. Information gathered from the developmental phase will inform the intervention. The intervention phase will determine the feasibility and efficacy of a multi-component dog walking intervention using a group randomized controlled trial. The intervention uses a social networking website, newsletters, pedometers, neighborhood walks, and community events to educate owners on the benefits of walking, create a supportive environment, and increase the “dog friendliness” of a community. Communities in Worcester and Lowell will be randomized to the intervention or control condition. Outcome measures include pedometer steps, time spent walking the dog, social support for exercise, and sense of community. This study is one of the first studies to test whether increasing dog walking in dog owners can increase owner physical activity via a social networking website. If successful, we will assess the extent to which the community can sustain the intervention

A LOV Protein Modulates the Physiological Attributes of Xanthomonas axonopodis pv. citri Relevant for Host Plant Colonization

Recent studies have demonstrated that an appropriate light environment is required for the establishment of efficient vegetal resistance responses in several plant-pathogen interactions. The photoreceptors implicated in such responses are mainly those belonging to the phytochrome family. Data obtained from bacterial genome sequences revealed the presence of photosensory proteins of the BLUF (Blue Light sensing Using FAD), LOV (Light, Oxygen, Voltage) and phytochrome families with no known functions. Xanthomonas axonopodis pv. citri is a Gram-negative bacterium responsible for citrus canker. The in silico analysis of the X. axonopodis pv. citri genome sequence revealed the presence of a gene encoding a putative LOV photoreceptor, in addition to two genes encoding BLUF proteins. This suggests that blue light sensing could play a role in X. axonopodis pv. citri physiology. We obtained the recombinant Xac-LOV protein by expression in Escherichia coli and performed a spectroscopic analysis of the purified protein, which demonstrated that it has a canonical LOV photochemistry. We also constructed a mutant strain of X. axonopodis pv. citri lacking the LOV protein and found that the loss of this protein altered bacterial motility, exopolysaccharide production and biofilm formation. Moreover, we observed that the adhesion of the mutant strain to abiotic and biotic surfaces was significantly diminished compared to the wild-type. Finally, inoculation of orange (Citrus sinensis) leaves with the mutant strain of X. axonopodis pv. citri resulted in marked differences in the development of symptoms in plant tissues relative to the wild-type, suggesting a role for the Xac-LOV protein in the pathogenic process. Altogether, these results suggest the novel involvement of a photosensory system in the regulation of physiological attributes of a phytopathogenic bacterium. A functional blue light receptor in Xanthomonas spp. has been described for the first time, showing an important role in virulence during citrus canker disease

Breakout Session: Paths to Obtaining Funding for Community Engaged Research

Discusses the UMass CCTS Community Engagement & Research Section Pilot/Feasibility Grants Program and other potential sources of funding for community engaged research

Marketplace commodification of risk communication: Consequences for risk bearers and implications for public relations

Society’s attempt to understand and communicate about risk is perhaps the world’s oldest topic − the rationale for human existence and survival (Douglas, 1992). This paper takes critical stock of public relations scholarship and practices in the daunting complex that has become known as the infrastructural approach to risk communication. This approach blends critical judgment of the community structures where risk is discussed and the discourse in which it is analyzed as the foundation for risk governance needed for fully functioning societies. The critical lens of hegemony and postmodernism reveals how an increasing amount of risk communication scholarship and practice has evolved into a new professional, industrial, and societal hegemony that often marginalizes risk bearers and risk arbiters as a nuisance in an otherwise modern and elitist approach to risk control through which risk communication becomes a “priced commodity.” Such commodification can empower organizations to take further risks because of the perceived confidence that its robust risk management programs and risk communication teams, including public relations, can control the dialogue and thereby help protect it from business continuity failure. The great challenge is whether risk communication and management ultimately favors the interests of elites over, and even to the marginalization and subjugation of, the interests of risk bearers and arbiters, ignoring the experiences of inequalities over the life span

The RADx Tech Clinical Studies Core: A Model for Academic Based Clinical Studies

The National Institutes of Health (NIH) launched the Rapid Acceleration of Diagnostics (RADx SM ) Tech initiative to support the development and commercialization of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) point-of-care test devices. The primary objective of the Clinical Studies Core (CSC) was to perform SARS-CoV-2 device studies involving diverse populations and settings. Within a few months, the infrastructure for clinical studies was developed, including a master protocol, digital study platform, data management system, single IRB, and multi-site partnerships. Data from some studies are being used to support Emergency Use Authorization of novel SARS-CoV-2 test devices. The CSC reduced the typical time and cost of developing medical devices and highlighted the impactful role of academic and NIH partnership in addressing public health needs at a rapid pace during a global pandemic. The structure, deployment, and lessons learned from this experience are widely applicable to future in vitro diagnostic device clinical studies